Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining S...

Descripción completa

Detalles Bibliográficos
Autores principales: Valenzise, Mariella, Aversa, Tommaso, Zirilli, Giuseppina, Salzano, Giuseppina, Corica, Domenico, Santucci, Simona, De Luca, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209824/
https://www.ncbi.nlm.nih.gov/pubmed/28049529
http://dx.doi.org/10.1186/s13052-016-0322-z
Descripción
Sumario:Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining SH even after a prolonged follow-up. By contrast, the risk of a significant deterioration of thyroid status is distinctly higher in the SH children with Hashimoto’s thyroiditis (HT). This risk is even higher in the cases with both HT-related SH and chromosomal abnormalities, such as Turner or Down’s syndrome.

Ejemplares similares