Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining S...

Descripción completa

Detalles Bibliográficos
Autores principales: Valenzise, Mariella, Aversa, Tommaso, Zirilli, Giuseppina, Salzano, Giuseppina, Corica, Domenico, Santucci, Simona, De Luca, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209824/
https://www.ncbi.nlm.nih.gov/pubmed/28049529
http://dx.doi.org/10.1186/s13052-016-0322-z
_version_ 1782490800174661632
author Valenzise, Mariella
Aversa, Tommaso
Zirilli, Giuseppina
Salzano, Giuseppina
Corica, Domenico
Santucci, Simona
De Luca, Filippo
author_facet Valenzise, Mariella
Aversa, Tommaso
Zirilli, Giuseppina
Salzano, Giuseppina
Corica, Domenico
Santucci, Simona
De Luca, Filippo
author_sort Valenzise, Mariella
collection PubMed
description Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining SH even after a prolonged follow-up. By contrast, the risk of a significant deterioration of thyroid status is distinctly higher in the SH children with Hashimoto’s thyroiditis (HT). This risk is even higher in the cases with both HT-related SH and chromosomal abnormalities, such as Turner or Down’s syndrome.
format Online
Article
Text
id pubmed-5209824
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-52098242017-01-04 Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children Valenzise, Mariella Aversa, Tommaso Zirilli, Giuseppina Salzano, Giuseppina Corica, Domenico Santucci, Simona De Luca, Filippo Ital J Pediatr Commentary Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining SH even after a prolonged follow-up. By contrast, the risk of a significant deterioration of thyroid status is distinctly higher in the SH children with Hashimoto’s thyroiditis (HT). This risk is even higher in the cases with both HT-related SH and chromosomal abnormalities, such as Turner or Down’s syndrome. BioMed Central 2017-01-03 /pmc/articles/PMC5209824/ /pubmed/28049529 http://dx.doi.org/10.1186/s13052-016-0322-z Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Valenzise, Mariella
Aversa, Tommaso
Zirilli, Giuseppina
Salzano, Giuseppina
Corica, Domenico
Santucci, Simona
De Luca, Filippo
Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
title Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
title_full Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
title_fullStr Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
title_full_unstemmed Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
title_short Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
title_sort analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209824/
https://www.ncbi.nlm.nih.gov/pubmed/28049529
http://dx.doi.org/10.1186/s13052-016-0322-z
work_keys_str_mv AT valenzisemariella analysisofthefactorsaffectingtheevolutionovertimeofsubclinicalhypothyroidisminchildren
AT aversatommaso analysisofthefactorsaffectingtheevolutionovertimeofsubclinicalhypothyroidisminchildren
AT zirilligiuseppina analysisofthefactorsaffectingtheevolutionovertimeofsubclinicalhypothyroidisminchildren
AT salzanogiuseppina analysisofthefactorsaffectingtheevolutionovertimeofsubclinicalhypothyroidisminchildren
AT coricadomenico analysisofthefactorsaffectingtheevolutionovertimeofsubclinicalhypothyroidisminchildren
AT santuccisimona analysisofthefactorsaffectingtheevolutionovertimeofsubclinicalhypothyroidisminchildren
AT delucafilippo analysisofthefactorsaffectingtheevolutionovertimeofsubclinicalhypothyroidisminchildren

Ejemplares similares