Improvement of whole-cell transamination with Saccharomyces cerevisiae using metabolic engineering and cell pre-adaptation

BACKGROUND: Whole-cell biocatalysis based on metabolically active baker’s yeast with engineered transamination activity can be used to generate molecules carrying a chiral amine moiety. A prerequisite is though to express efficient ω-transaminases and to reach sufficient intracellular precursor leve...

Descripción completa

Detalles Bibliográficos
Autores principales: Weber, Nora, Gorwa-Grauslund, Marie, Carlquist, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209827/
https://www.ncbi.nlm.nih.gov/pubmed/28049528
http://dx.doi.org/10.1186/s12934-016-0615-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209827/
https://www.ncbi.nlm.nih.gov/pubmed/28049528
http://dx.doi.org/10.1186/s12934-016-0615-3

Ejemplares similares