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Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway

Coenzyme Q (CoQ) is an electron acceptor for sulfide‐quinone reductase (SQR), the first enzyme of the hydrogen sulfide oxidation pathway. Here, we show that lack of CoQ in human skin fibroblasts causes impairment of hydrogen sulfide oxidation, proportional to the residual levels of CoQ. Biochemical...

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Detalles Bibliográficos
Autores principales: Ziosi, Marcello, Di Meo, Ivano, Kleiner, Giulio, Gao, Xing‐Huang, Barca, Emanuele, Sanchez‐Quintero, Maria J, Tadesse, Saba, Jiang, Hongfeng, Qiao, Changhong, Rodenburg, Richard J, Scalais, Emmanuel, Schuelke, Markus, Willard, Belinda, Hatzoglou, Maria, Tiranti, Valeria, Quinzii, Catarina M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210092/
https://www.ncbi.nlm.nih.gov/pubmed/27856618
http://dx.doi.org/10.15252/emmm.201606356