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A mixed-integer linear programming approach to the reduction of genome-scale metabolic networks
BACKGROUND: Constraint-based analysis has become a widely used method to study metabolic networks. While some of the associated algorithms can be applied to genome-scale network reconstructions with several thousands of reactions, others are limited to small or medium-sized models. In 2015, Erdrich...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210269/ https://www.ncbi.nlm.nih.gov/pubmed/28049424 http://dx.doi.org/10.1186/s12859-016-1412-z |