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MiR‐590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte‐Like Fate by Directly Repressing Specificity Protein 1

BACKGROUND: Reprogramming of cardiac fibroblasts into induced cardiomyocyte‐like cells represents a promising potential new therapy for treating heart disease, inducing significant improvements in postinfarct ventricular function in rodent models. Because reprogramming factors effective in transdiff...

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Detalles Bibliográficos
Autores principales:	Singh, Vivek P., Mathison, Megumi, Patel, Vivekkumar, Sanagasetti, Deepthi, Gibson, Brian W., Yang, Jianchang, Rosengart, Todd K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210349/ https://www.ncbi.nlm.nih.gov/pubmed/27930352 http://dx.doi.org/10.1161/JAHA.116.003922

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