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The portal‐drained viscera release fibroblast growth factor 19 in humans

Fibroblast growth factor 19 (FGF19) is an ileum‐derived endrocrine factor that is produced in response to transepithelial bile salt flux. FGF19 represses bile salt synthesis in the liver. Despite the general assumption that FGF19 signals to the liver via portal blood, no human data are available to...

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Detalles Bibliográficos
Autores principales: Koelfat, Kiran V. K., Bloemen, Johanne G., Jansen, Peter L. M., Dejong, Cornelis H. C., Schaap, Frank G., Olde Damink, Steven W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210390/
https://www.ncbi.nlm.nih.gov/pubmed/28003563
http://dx.doi.org/10.14814/phy2.13037