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Ischemic Preconditioning Confers Epigenetic Repression of Mtor and Induction of Autophagy Through G9a‐Dependent H3K9 Dimethylation

BACKGROUND: Ischemic preconditioning (IPC) protects the heart from prolonged ischemic insult and reperfusion injury through a poorly understood mechanism. Post‐translational modifications of histone residues can confer rapid and drastic switches in gene expression in response to various stimuli, inc...

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Detalles Bibliográficos
Autores principales: Gidlöf, Olof, Johnstone, Andrea L., Bader, Kerstin, Khomtchouk, Bohdan B., O'Reilly, Jiaqi J., Celik, Selvi, Van Booven, Derek J., Wahlestedt, Claes, Metzler, Bernhard, Erlinge, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210409/
https://www.ncbi.nlm.nih.gov/pubmed/28007739
http://dx.doi.org/10.1161/JAHA.116.004076

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