Cargando…

Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation

BACKGROUND: Although several studies have reported an association between atrial fibrillation (AF) and alcohol, the impact of alcohol consumption on the outcome after catheter ablation (CA) for AF has not been discussed. We aimed to elucidate the effect of alcohol consumption on the outcome of CA fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Takigawa, Masateru, Takahashi, Atsushi, Kuwahara, Taishi, Takahashi, Yoshihide, Okubo, Kenji, Nakashima, Emiko, Watari, Yuji, Nakajima, Jun, Yamao, Kazuya, Osaka, Yuki, Tanaka, Yasuaki, Kimura, Shigeki, Takagi, Katsumasa, Hikita, Hiroyuki, Hirao, Kenzo, Isobe, Mitsuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210418/
https://www.ncbi.nlm.nih.gov/pubmed/27895043
http://dx.doi.org/10.1161/JAHA.116.004149
_version_ 1782490883061448704
author Takigawa, Masateru
Takahashi, Atsushi
Kuwahara, Taishi
Takahashi, Yoshihide
Okubo, Kenji
Nakashima, Emiko
Watari, Yuji
Nakajima, Jun
Yamao, Kazuya
Osaka, Yuki
Tanaka, Yasuaki
Kimura, Shigeki
Takagi, Katsumasa
Hikita, Hiroyuki
Hirao, Kenzo
Isobe, Mitsuaki
author_facet Takigawa, Masateru
Takahashi, Atsushi
Kuwahara, Taishi
Takahashi, Yoshihide
Okubo, Kenji
Nakashima, Emiko
Watari, Yuji
Nakajima, Jun
Yamao, Kazuya
Osaka, Yuki
Tanaka, Yasuaki
Kimura, Shigeki
Takagi, Katsumasa
Hikita, Hiroyuki
Hirao, Kenzo
Isobe, Mitsuaki
author_sort Takigawa, Masateru
collection PubMed
description BACKGROUND: Although several studies have reported an association between atrial fibrillation (AF) and alcohol, the impact of alcohol consumption on the outcome after catheter ablation (CA) for AF has not been discussed. We aimed to elucidate the effect of alcohol consumption on the outcome of CA for paroxysmal AF. METHODS AND RESULTS: We examined 1361 consecutive patients with paroxysmal AF (mean age, 61±11 years, 334 women) who underwent CA, including 623 (45.8%) patients who consumed alcohol. The clinical characteristics and outcomes of CA were compared between patients who did and did not consume alcohol. No significant differences were seen in the left atrial size, duration of AF history, and incidence of nonpulmonary vein foci between 2 groups (P=NS). Although the AF recurrence‐free rate after the initial CA was higher in patients who did not consume alcohol (261/623 [41.9%] versus 252/738 [34.1%]; mean follow‐up, 44.4±30.7 months; P=0.003), the outcome after the final CA was similar between 2 groups (patients who consumed alcohol: 111/628 [17.7%] versus patients who did not consume alcohol: 138/738 [18.7%]; mean follow‐up, 53.1±25.8 months; P=0.67). The frequency (hazard ratio 1.07 per 1 day/week increase, CI 1.00–1.15, P=0.04) of alcohol consumption was significantly associated with AF recurrence after CA. CONCLUSIONS: The frequency of alcohol consumption may be associated with AF recurrence after the initial CA for paroxysmal AF, but it may not affect the outcome after the final CA.
format Online
Article
Text
id pubmed-5210418
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-52104182017-01-05 Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation Takigawa, Masateru Takahashi, Atsushi Kuwahara, Taishi Takahashi, Yoshihide Okubo, Kenji Nakashima, Emiko Watari, Yuji Nakajima, Jun Yamao, Kazuya Osaka, Yuki Tanaka, Yasuaki Kimura, Shigeki Takagi, Katsumasa Hikita, Hiroyuki Hirao, Kenzo Isobe, Mitsuaki J Am Heart Assoc Original Research BACKGROUND: Although several studies have reported an association between atrial fibrillation (AF) and alcohol, the impact of alcohol consumption on the outcome after catheter ablation (CA) for AF has not been discussed. We aimed to elucidate the effect of alcohol consumption on the outcome of CA for paroxysmal AF. METHODS AND RESULTS: We examined 1361 consecutive patients with paroxysmal AF (mean age, 61±11 years, 334 women) who underwent CA, including 623 (45.8%) patients who consumed alcohol. The clinical characteristics and outcomes of CA were compared between patients who did and did not consume alcohol. No significant differences were seen in the left atrial size, duration of AF history, and incidence of nonpulmonary vein foci between 2 groups (P=NS). Although the AF recurrence‐free rate after the initial CA was higher in patients who did not consume alcohol (261/623 [41.9%] versus 252/738 [34.1%]; mean follow‐up, 44.4±30.7 months; P=0.003), the outcome after the final CA was similar between 2 groups (patients who consumed alcohol: 111/628 [17.7%] versus patients who did not consume alcohol: 138/738 [18.7%]; mean follow‐up, 53.1±25.8 months; P=0.67). The frequency (hazard ratio 1.07 per 1 day/week increase, CI 1.00–1.15, P=0.04) of alcohol consumption was significantly associated with AF recurrence after CA. CONCLUSIONS: The frequency of alcohol consumption may be associated with AF recurrence after the initial CA for paroxysmal AF, but it may not affect the outcome after the final CA. John Wiley and Sons Inc. 2016-11-28 /pmc/articles/PMC5210418/ /pubmed/27895043 http://dx.doi.org/10.1161/JAHA.116.004149 Text en © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Takigawa, Masateru
Takahashi, Atsushi
Kuwahara, Taishi
Takahashi, Yoshihide
Okubo, Kenji
Nakashima, Emiko
Watari, Yuji
Nakajima, Jun
Yamao, Kazuya
Osaka, Yuki
Tanaka, Yasuaki
Kimura, Shigeki
Takagi, Katsumasa
Hikita, Hiroyuki
Hirao, Kenzo
Isobe, Mitsuaki
Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
title Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
title_full Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
title_fullStr Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
title_full_unstemmed Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
title_short Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
title_sort impact of alcohol consumption on the outcome of catheter ablation in patients with paroxysmal atrial fibrillation
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210418/
https://www.ncbi.nlm.nih.gov/pubmed/27895043
http://dx.doi.org/10.1161/JAHA.116.004149
work_keys_str_mv AT takigawamasateru impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT takahashiatsushi impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT kuwaharataishi impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT takahashiyoshihide impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT okubokenji impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT nakashimaemiko impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT watariyuji impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT nakajimajun impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT yamaokazuya impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT osakayuki impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT tanakayasuaki impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT kimurashigeki impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT takagikatsumasa impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT hikitahiroyuki impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT hiraokenzo impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation
AT isobemitsuaki impactofalcoholconsumptionontheoutcomeofcatheterablationinpatientswithparoxysmalatrialfibrillation