Updates in Rhea – an expert curated resource of biochemical reactions

Mostrar otras versiones (1)

Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the description of metabolic networks. Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as we...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgat, Anne, Lombardot, Thierry, Axelsen, Kristian B., Aimo, Lucila, Niknejad, Anne, Hyka-Nouspikel, Nevila, Coudert, Elisabeth, Pozzato, Monica, Pagni, Marco, Moretti, Sébastien, Rosanoff, Steven, Onwubiko, Joseph, Bougueleret, Lydie, Xenarios, Ioannis, Redaschi, Nicole, Bridge, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210663/
https://www.ncbi.nlm.nih.gov/pubmed/27789701
http://dx.doi.org/10.1093/nar/gkw990
_version_ 1782490930577670144
author Morgat, Anne
Lombardot, Thierry
Axelsen, Kristian B.
Aimo, Lucila
Niknejad, Anne
Hyka-Nouspikel, Nevila
Coudert, Elisabeth
Pozzato, Monica
Pagni, Marco
Moretti, Sébastien
Rosanoff, Steven
Onwubiko, Joseph
Bougueleret, Lydie
Xenarios, Ioannis
Redaschi, Nicole
Bridge, Alan
author_facet Morgat, Anne
Lombardot, Thierry
Axelsen, Kristian B.
Aimo, Lucila
Niknejad, Anne
Hyka-Nouspikel, Nevila
Coudert, Elisabeth
Pozzato, Monica
Pagni, Marco
Moretti, Sébastien
Rosanoff, Steven
Onwubiko, Joseph
Bougueleret, Lydie
Xenarios, Ioannis
Redaschi, Nicole
Bridge, Alan
author_sort Morgat, Anne
collection PubMed
description Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the description of metabolic networks. Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as well as additional reactions, including spontaneously occurring reactions, using entities from the ChEBI (Chemical Entities of Biological Interest) ontology of small molecules. Here we describe developments in Rhea since our last report in the database issue of Nucleic Acids Research. These include the first implementation of a simple hierarchical classification of reactions, improved coverage of the IUBMB Enzyme Nomenclature list and additional reactions through continuing expert curation, and the development of a new website to serve this improved dataset.
format Online
Article
Text
id pubmed-5210663
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-52106632017-01-05 Updates in Rhea – an expert curated resource of biochemical reactions Morgat, Anne Lombardot, Thierry Axelsen, Kristian B. Aimo, Lucila Niknejad, Anne Hyka-Nouspikel, Nevila Coudert, Elisabeth Pozzato, Monica Pagni, Marco Moretti, Sébastien Rosanoff, Steven Onwubiko, Joseph Bougueleret, Lydie Xenarios, Ioannis Redaschi, Nicole Bridge, Alan Nucleic Acids Res Database Issue Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the description of metabolic networks. Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as well as additional reactions, including spontaneously occurring reactions, using entities from the ChEBI (Chemical Entities of Biological Interest) ontology of small molecules. Here we describe developments in Rhea since our last report in the database issue of Nucleic Acids Research. These include the first implementation of a simple hierarchical classification of reactions, improved coverage of the IUBMB Enzyme Nomenclature list and additional reactions through continuing expert curation, and the development of a new website to serve this improved dataset. Oxford University Press 2017-01-04 2016-10-26 /pmc/articles/PMC5210663/ /pubmed/27789701 http://dx.doi.org/10.1093/nar/gkw990 Text en © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Morgat, Anne
Lombardot, Thierry
Axelsen, Kristian B.
Aimo, Lucila
Niknejad, Anne
Hyka-Nouspikel, Nevila
Coudert, Elisabeth
Pozzato, Monica
Pagni, Marco
Moretti, Sébastien
Rosanoff, Steven
Onwubiko, Joseph
Bougueleret, Lydie
Xenarios, Ioannis
Redaschi, Nicole
Bridge, Alan
Updates in Rhea – an expert curated resource of biochemical reactions
title Updates in Rhea – an expert curated resource of biochemical reactions
title_full Updates in Rhea – an expert curated resource of biochemical reactions
title_fullStr Updates in Rhea – an expert curated resource of biochemical reactions
title_full_unstemmed Updates in Rhea – an expert curated resource of biochemical reactions
title_short Updates in Rhea – an expert curated resource of biochemical reactions
title_sort updates in rhea – an expert curated resource of biochemical reactions
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210663/
https://www.ncbi.nlm.nih.gov/pubmed/27789701
http://dx.doi.org/10.1093/nar/gkw990
work_keys_str_mv AT morgatanne updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT lombardotthierry updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT axelsenkristianb updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT aimolucila updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT niknejadanne updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT hykanouspikelnevila updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT coudertelisabeth updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT pozzatomonica updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT pagnimarco updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT morettisebastien updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT rosanoffsteven updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT onwubikojoseph updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT bougueleretlydie updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT xenariosioannis updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT redaschinicole updatesinrheaanexpertcuratedresourceofbiochemicalreactions
AT bridgealan updatesinrheaanexpertcuratedresourceofbiochemicalreactions

Ejemplares similares