DJ-1 Is a Redox-Dependent Molecular Chaperone That Inhibits α-Synuclein Aggregate Formation

Parkinson's disease (PD) pathology is characterized by the degeneration of midbrain dopamine neurons (DNs) ultimately leading to a progressive movement disorder in patients. The etiology of DN loss in sporadic PD is unknown, although it is hypothesized that aberrant protein aggregation and cell...

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Detalles Bibliográficos
Autores principales: Shendelman, Shoshana, Jonason, Alan, Martinat, Cecile, Leete, Thomas, Abeliovich, Asa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC521177/
https://www.ncbi.nlm.nih.gov/pubmed/15502874
http://dx.doi.org/10.1371/journal.pbio.0020362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC521177/
https://www.ncbi.nlm.nih.gov/pubmed/15502874
http://dx.doi.org/10.1371/journal.pbio.0020362

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