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Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma

Intrinsically disordered proteins (IDPs) are prevalent in eukaryotes, performing signaling and regulatory functions. Often associated with human diseases, they constitute drug-development targets. NUPR1 is a multifunctional IDP, over-expressed and involved in pancreatic ductal adenocarcinoma (PDAC)...

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Detalles Bibliográficos
Autores principales:	Neira, José L., Bintz, Jennifer, Arruebo, María, Rizzuti, Bruno, Bonacci, Thomas, Vega, Sonia, Lanas, Angel, Velázquez-Campoy, Adrián, Iovanna, Juan L., Abián, Olga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213423/ https://www.ncbi.nlm.nih.gov/pubmed/28054562 http://dx.doi.org/10.1038/srep39732

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