Voltage-Dependent Inactivation of MscS Occurs Independently of the Positively Charged Residues in the Transmembrane Domain

MscS (mechanosensitive channel of small conductance) is ubiquitously found among bacteria and plays a major role in avoiding cell lysis upon rapid osmotic downshock. The gating of MscS is modulated by voltage, but little is known about how MscS senses membrane potential. Three arginine residues (Arg...

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Detalles Bibliográficos
Autores principales: Nomura, Takeshi, Sokabe, Masahiro, Yoshimura, Kenjiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213669/
https://www.ncbi.nlm.nih.gov/pubmed/28101504
http://dx.doi.org/10.1155/2016/2401657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213669/
https://www.ncbi.nlm.nih.gov/pubmed/28101504
http://dx.doi.org/10.1155/2016/2401657

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