Cargando…

Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase

Cyclohexanone monooxygenase (CHMO) is a promising biocatalyst for industrial reactions owing to its broad substrate spectrum and excellent regio‐, chemo‐, and enantioselectivity. However, the low stability of many Baeyer–Villiger monooxygenases is an obstacle for their exploitation in industry. Char...

Descripción completa

Detalles Bibliográficos
Autores principales:	Romero, Elvira, Castellanos, J. Rubén Gómez, Mattevi, Andrea, Fraaije, Marco W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213842/ https://www.ncbi.nlm.nih.gov/pubmed/27873437 http://dx.doi.org/10.1002/anie.201608951

Ejemplares similares

Stabilization of cyclohexanone monooxygenase by computational and experimental library design
por: Fürst, Maximilian J. L. J., et al.
Publicado: (2019)

Coupled reactions by coupled enzymes: alcohol to lactone cascade with alcohol dehydrogenase–cyclohexanone monooxygenase fusions
por: Aalbers, Friso S., et al.
Publicado: (2017)

Stabilization of cyclohexanone monooxygenase by a computationally designed disulfide bond spanning only one residue
por: van Beek, Hugo L., et al.
Publicado: (2014)

Evolution of enzyme functionality in the flavin-containing monooxygenases
por: Bailleul, Gautier, et al.
Publicado: (2023)

In Vivo, High-Throughput Selection of Thermostable Cyclohexanone Monooxygenase (CHMO)
por: Maxel, Sarah, et al.
Publicado: (2020)

Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme
por: Fürst, Maximilian J. L. J., et al.
Publicado: (2018)

Calorimetric and Computational Study of Enthalpy of Formation of Diperoxide of Cyclohexanone
por: Romero, Jorge Marcelo, et al.
Publicado: (2007)

Structure-Based Redesign of a Self-Sufficient Flavin-Containing Monooxygenase towards Indigo Production
por: Lončar, Nikola, et al.
Publicado: (2019)

Structure-Based Engineering of Phanerochaete chrysosporium Alcohol Oxidase for Enhanced Oxidative Power toward Glycerol
por: Nguyen, Quoc-Thai, et al.
Publicado: (2018)

Modular Assembly of Phosphite Dehydrogenase and Phenylacetone Monooxygenase for Tuning Cofactor Regeneration
por: Purwani, Ni Nyoman, et al.
Publicado: (2021)

Adsorptive separation of cyclohexanol and cyclohexanone by nonporous adaptive crystals of RhombicArene
por: Zhao, Yongye, et al.
Publicado: (2021)

Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering
por: Aalbers, Friso S, et al.
Publicado: (2020)

Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2
por: Stewart, Andrew, et al.
Publicado: (2023)

Enzyme cascade converting cyclohexanol into ε‐caprolactone coupled with NADPH recycling using surface displayed alcohol dehydrogenase and cyclohexanone monooxygenase on E. coli
por: Tian, Haijin, et al.
Publicado: (2022)

Discovery and characterization of an F(420)-dependent glucose-6-phosphate dehydrogenase (Rh-FGD1) from Rhodococcus jostii RHA1
por: Nguyen, Quoc-Thai, et al.
Publicado: (2016)

Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca
por: Dudek, Hanna M., et al.
Publicado: (2010)

Enantioselective Desymmetrization of Prochiral Cyclohexanones by Organocatalytic Intramolecular Michael Additions to α,β-Unsaturated Esters**
por: Gammack Yamagata, Adam D, et al.
Publicado: (2015)

Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile
por: Zhang, Y., et al.
Publicado: (2011)

Dual catalytic enantioselective desymmetrization of allene-tethered cyclohexanones
por: Zhang, Lin, et al.
Publicado: (2020)

Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties
por: Bailleul, Gautier, et al.
Publicado: (2020)

Mining the Genome of Streptomyces leeuwenhoekii: Two New Type I Baeyer–Villiger Monooxygenases From Atacama Desert
por: Gran-Scheuch, Alejandro, et al.
Publicado: (2018)

Associative behavior of polyimide/cyclohexanone solutions
por: Chen, Hongxiang, et al.
Publicado: (2019)

Cyclohexanone-Based Chalcones as Alternatives for Fuel Additives
por: Sallum, Lóide O., et al.
Publicado: (2022)

Discovery, Biocatalytic Exploration and Structural Analysis of a 4‐Ethylphenol Oxidase from Gulosibacter chungangensis
por: Alvigini, Laura, et al.
Publicado: (2021)

Cloning, overexpression and biocatalytic exploration of a novel Baeyer-Villiger monooxygenase from Aspergillus fumigatus Af293
por: Mascotti, Maria Laura, et al.
Publicado: (2013)

Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst
por: Nguyen, Quoc‐Thai, et al.
Publicado: (2016)

Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase
por: Boverio, Alessandro, et al.
Publicado: (2022)

Erratum to: Cloning, overexpression and biocatalytic exploration of a novel Baeyer-Villiger monooxygenase from Aspergillus fumigatus Af293
por: Mascotti, Maria Laura, et al.
Publicado: (2014)

Seed-assisted synthesis of TS-1 crystals containing Al with high catalytic performances in cyclohexanone ammoximation
por: Xue, Yan, et al.
Publicado: (2019)

A Benchmark of Density Functional Approximations For Thermochemistry and Kinetics of Hydride Reductions of Cyclohexanones
por: Deraet, Xavier, et al.
Publicado: (2019)

Structural and Catalytic Characterization of a Fungal Baeyer-Villiger Monooxygenase
por: Ferroni, Felix Martin, et al.
Publicado: (2016)

Expanding the set of rhodococcal Baeyer–Villiger monooxygenases by high-throughput cloning, expression and substrate screening
por: Riebel, A., et al.
Publicado: (2012)

Cyclohexanone 2-nitrophenylhydrazone
por: Yang, Bao-he, et al.
Publicado: (2010)

The oxygenating constituent of 3,6-diketocamphane monooxygenase from the CAM plasmid of Pseudomonas putida: the first crystal structure of a type II Baeyer–Villiger monooxygenase
por: Isupov, Michail N., et al.
Publicado: (2015)

A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center
por: Rotilio, Laura, et al.
Publicado: (2023)

Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound
por: Guo, Yiming, et al.
Publicado: (2022)

Design of Artificial Alcohol Oxidases: Alcohol Dehydrogenase–NADPH Oxidase Fusions for Continuous Oxidations
por: Aalbers, Friso S., et al.
Publicado: (2018)

The Substrate-Bound Crystal Structure of a Baeyer–Villiger Monooxygenase Exhibits a Criegee-like Conformation
por: Yachnin, Brahm J., et al.
Publicado: (2012)

On the functional characterization of lytic polysaccharide monooxygenases (LPMOs)
por: Eijsink, Vincent G. H., et al.
Publicado: (2019)

Functional and structural characterization of a flavoprotein monooxygenase essential for biogenesis of tryptophylquinone cofactor
por: Oozeki, Toshinori, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kb9sdnrqkgkijf59fqo8j6o2ln