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Burns: Pathophysiology of Systemic Complications and Current Management

As a result of many years of research, the intricate cellular mechanisms of burn injury are slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of resulting studies have often failed to translate into improved clinical treatment for burn injuries. Perhaps the most valu...

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Detalles Bibliográficos
Autores principales: Nielson, Colton B., Duethman, Nicholas C., Howard, James M., Moncure, Michael, Wood, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214064/
https://www.ncbi.nlm.nih.gov/pubmed/27183443
http://dx.doi.org/10.1097/BCR.0000000000000355
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author Nielson, Colton B.
Duethman, Nicholas C.
Howard, James M.
Moncure, Michael
Wood, John G.
author_facet Nielson, Colton B.
Duethman, Nicholas C.
Howard, James M.
Moncure, Michael
Wood, John G.
author_sort Nielson, Colton B.
collection PubMed
description As a result of many years of research, the intricate cellular mechanisms of burn injury are slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of resulting studies have often failed to translate into improved clinical treatment for burn injuries. Perhaps the most valuable information to date is the years of clinical experience and observations in the management and treatment of patients, which has contributed to a gradual improvement in reported outcomes of mortality. This review provides a discussion of the cellular mechanisms and pathways involved in burn injury, resultant systemic effects on organ systems, current management and treatment, and potential therapies that we may see implemented in the future.
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spelling pubmed-52140642017-01-17 Burns: Pathophysiology of Systemic Complications and Current Management Nielson, Colton B. Duethman, Nicholas C. Howard, James M. Moncure, Michael Wood, John G. J Burn Care Res Summary Articles As a result of many years of research, the intricate cellular mechanisms of burn injury are slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of resulting studies have often failed to translate into improved clinical treatment for burn injuries. Perhaps the most valuable information to date is the years of clinical experience and observations in the management and treatment of patients, which has contributed to a gradual improvement in reported outcomes of mortality. This review provides a discussion of the cellular mechanisms and pathways involved in burn injury, resultant systemic effects on organ systems, current management and treatment, and potential therapies that we may see implemented in the future. Lippincott Williams & Wilkins 2017-01 2016-12-22 /pmc/articles/PMC5214064/ /pubmed/27183443 http://dx.doi.org/10.1097/BCR.0000000000000355 Text en Copyright © 2016 by the American Burn Association This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Summary Articles
Nielson, Colton B.
Duethman, Nicholas C.
Howard, James M.
Moncure, Michael
Wood, John G.
Burns: Pathophysiology of Systemic Complications and Current Management
title Burns: Pathophysiology of Systemic Complications and Current Management
title_full Burns: Pathophysiology of Systemic Complications and Current Management
title_fullStr Burns: Pathophysiology of Systemic Complications and Current Management
title_full_unstemmed Burns: Pathophysiology of Systemic Complications and Current Management
title_short Burns: Pathophysiology of Systemic Complications and Current Management
title_sort burns: pathophysiology of systemic complications and current management
topic Summary Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214064/
https://www.ncbi.nlm.nih.gov/pubmed/27183443
http://dx.doi.org/10.1097/BCR.0000000000000355
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