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Burns: Pathophysiology of Systemic Complications and Current Management
As a result of many years of research, the intricate cellular mechanisms of burn injury are slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of resulting studies have often failed to translate into improved clinical treatment for burn injuries. Perhaps the most valu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214064/ https://www.ncbi.nlm.nih.gov/pubmed/27183443 http://dx.doi.org/10.1097/BCR.0000000000000355 |
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author | Nielson, Colton B. Duethman, Nicholas C. Howard, James M. Moncure, Michael Wood, John G. |
author_facet | Nielson, Colton B. Duethman, Nicholas C. Howard, James M. Moncure, Michael Wood, John G. |
author_sort | Nielson, Colton B. |
collection | PubMed |
description | As a result of many years of research, the intricate cellular mechanisms of burn injury are slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of resulting studies have often failed to translate into improved clinical treatment for burn injuries. Perhaps the most valuable information to date is the years of clinical experience and observations in the management and treatment of patients, which has contributed to a gradual improvement in reported outcomes of mortality. This review provides a discussion of the cellular mechanisms and pathways involved in burn injury, resultant systemic effects on organ systems, current management and treatment, and potential therapies that we may see implemented in the future. |
format | Online Article Text |
id | pubmed-5214064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-52140642017-01-17 Burns: Pathophysiology of Systemic Complications and Current Management Nielson, Colton B. Duethman, Nicholas C. Howard, James M. Moncure, Michael Wood, John G. J Burn Care Res Summary Articles As a result of many years of research, the intricate cellular mechanisms of burn injury are slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of resulting studies have often failed to translate into improved clinical treatment for burn injuries. Perhaps the most valuable information to date is the years of clinical experience and observations in the management and treatment of patients, which has contributed to a gradual improvement in reported outcomes of mortality. This review provides a discussion of the cellular mechanisms and pathways involved in burn injury, resultant systemic effects on organ systems, current management and treatment, and potential therapies that we may see implemented in the future. Lippincott Williams & Wilkins 2017-01 2016-12-22 /pmc/articles/PMC5214064/ /pubmed/27183443 http://dx.doi.org/10.1097/BCR.0000000000000355 Text en Copyright © 2016 by the American Burn Association This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Summary Articles Nielson, Colton B. Duethman, Nicholas C. Howard, James M. Moncure, Michael Wood, John G. Burns: Pathophysiology of Systemic Complications and Current Management |
title | Burns: Pathophysiology of Systemic Complications and Current Management |
title_full | Burns: Pathophysiology of Systemic Complications and Current Management |
title_fullStr | Burns: Pathophysiology of Systemic Complications and Current Management |
title_full_unstemmed | Burns: Pathophysiology of Systemic Complications and Current Management |
title_short | Burns: Pathophysiology of Systemic Complications and Current Management |
title_sort | burns: pathophysiology of systemic complications and current management |
topic | Summary Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214064/ https://www.ncbi.nlm.nih.gov/pubmed/27183443 http://dx.doi.org/10.1097/BCR.0000000000000355 |
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