Phosphorylation impact on Spleen Tyrosine kinase conformation by Surface Enhanced Raman Spectroscopy

Spleen Tyrosine Kinase (Syk) plays a crucial role in immune cell signalling and its altered expression or activation are involved in several cancers. Syk activity relies on its phosphorylation status and its multiple phosphorylation sites predict several Syk conformations. In this report, we charact...

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Detalles Bibliográficos
Autores principales: Cottat, Maximilien, Yasukuni, Ryohei, Homma, Yo, Lidgi-Guigui, Nathalie, Varin-Blank, Nadine, Lamy de la Chapelle, Marc, Le Roy, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214100/
https://www.ncbi.nlm.nih.gov/pubmed/28054556
http://dx.doi.org/10.1038/srep39766

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