Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes

Type 2 diabetes (T2D) is a global pandemic. Currently, the drugs used to treat T2D improve hyperglycemic symptom of the disease but the underlying mechanism causing the high blood glucose levels have not been fully resolved. Recently published data showed that salt form of niclosamide improved gluco...

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Detalles Bibliográficos
Autores principales: Chowdhury, Md. Kamrul Hasan, Turner, Nigel, Bentley, Nicholas L., Das, Abhirup, Wu, Lindsay E., Richani, Dulama, Bustamante, Sonia, Gilchrist, Robert B., Morris, Margaret J., Shepherd, Peter R., Smith, Greg C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214666/
https://www.ncbi.nlm.nih.gov/pubmed/28054648
http://dx.doi.org/10.1038/srep40159

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