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Attenuation of Compulsive-Like Behavior Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Non-Induced Compulsive-Like Mice

Nicotinic α4β2 receptors are the most abundant subtypes of nicotinic acetylcholine receptors (nAChRs) expressed in brain regions implicated in obsessive compulsive disorder (OCD). These receptors are known to modify normal and addictive behaviors by modulating neuronal excitability. Desformylflustra...

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Detalles Bibliográficos
Autores principales: Mitra, Swarup, Mucha, Mckenzie, Khatri, Shailesh N., Glenon, Richard, Schulte, Marvin K., Bult-Ito, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214813/
https://www.ncbi.nlm.nih.gov/pubmed/28105008
http://dx.doi.org/10.3389/fnbeh.2016.00244