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Attenuation of Compulsive-Like Behavior Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Non-Induced Compulsive-Like Mice
Nicotinic α4β2 receptors are the most abundant subtypes of nicotinic acetylcholine receptors (nAChRs) expressed in brain regions implicated in obsessive compulsive disorder (OCD). These receptors are known to modify normal and addictive behaviors by modulating neuronal excitability. Desformylflustra...
Autores principales: | Mitra, Swarup, Mucha, Mckenzie, Khatri, Shailesh N., Glenon, Richard, Schulte, Marvin K., Bult-Ito, Abel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214813/ https://www.ncbi.nlm.nih.gov/pubmed/28105008 http://dx.doi.org/10.3389/fnbeh.2016.00244 |
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