Betulin suppressed interleukin-1β-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat

We investigated whether betulin affects the gene expression, secretion and proteolytic activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the rat knee joint to evaluate the potential chondroprotective effect of...

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Detalles Bibliográficos
Autores principales: Ra, Ho Jong, Lee, Hyun Jae, Jo, Ho Seung, Nam, Dae Cheol, Lee, Young Bok, Kang, Byeong Hun, Moon, Dong Kyu, Kim, Dong Hee, Lee, Choong Jae, Hwang, Sun-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214907/
https://www.ncbi.nlm.nih.gov/pubmed/28066137
http://dx.doi.org/10.4196/kjpp.2017.21.1.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214907/
https://www.ncbi.nlm.nih.gov/pubmed/28066137
http://dx.doi.org/10.4196/kjpp.2017.21.1.19

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