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Intranasal Immunization Using Mannatide as a Novel Adjuvant for an Inactivated Influenza Vaccine and Its Adjuvant Effect Compared with MF59
Intranasal vaccination is more potent than parenteral injection for the prevention of influenza. However, because the poor efficiency of antigen uptake across the nasal mucosa is a key issue, immunostimulatory adjuvants are essential for intranasal vaccines. The immunomodulator mannatide or polyacti...
Autores principales: | Ren, Shu-Ting, Zhang, Xue-Mei, Sun, Peng-Fei, Sun, Li-Juan, Guo, Xue, Tian, Tian, Zhang, Jian, Guo, Qi-Yuan, Li, Xue, Guo, Li-Jun, Che, Jin, Wang, Bing, Zhang, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215226/ https://www.ncbi.nlm.nih.gov/pubmed/28052136 http://dx.doi.org/10.1371/journal.pone.0169501 |
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