Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A

Monophosphoryl lipid A (MPLA), a less toxic derivative of lipopolysaccharide (LPS), is employed as a vaccine adjuvant and is under investigation as a non-specific immunomodulator. However, the differential response of human leukocytes to MPLA and LPS has not been well characterized. The goal of this...

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Detalles Bibliográficos
Autores principales: Luan, Liming, Patil, Naeem K., Guo, Yin, Hernandez, Antonio, Bohannon, Julia K., Fensterheim, Benjamin A., Wang, Jingbin, Xu, Yaomin, Enkhbaatar, Perenlei, Stark, Ryan, Sherwood, Edward R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215261/
https://www.ncbi.nlm.nih.gov/pubmed/28053314
http://dx.doi.org/10.1038/srep40050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215261/
https://www.ncbi.nlm.nih.gov/pubmed/28053314
http://dx.doi.org/10.1038/srep40050

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