Human melanomas and ovarian cancers overexpressing mechanical barrier molecule genes lack immune signatures and have increased patient mortality risk

We have identified eight genes whose expression in human melanoma metastases and ovarian cancers is associated with a lack of Th1 immune signatures. They encode molecules with mechanical barrier function in the skin and other normal tissues and include filaggrin (FLG), tumor-associated calcium signa...

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Detalles Bibliográficos
Autores principales: Salerno, Elise P., Bedognetti, Davide, Mauldin, Ileana S., Deacon, Donna H., Shea, Sofia M., Pinczewski, Joel, Obeid, Joseph M., Coukos, George, Wang, Ena, Gajewski, Thomas F., Marincola, Francesco M., Slingluff, Craig L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215363/
https://www.ncbi.nlm.nih.gov/pubmed/28123876
http://dx.doi.org/10.1080/2162402X.2016.1240857

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