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Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour
How the dominant uncinate fasciculus (UF) contributes to naming performance is uncertain. In this case report, a patient with an astrocytoma near the dominant UF was given a picture-naming task during intraoperative electrical stimulation in order to resect as much tumourous tissues as possible with...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215405/ https://www.ncbi.nlm.nih.gov/pubmed/23242348 http://dx.doi.org/10.3233/BEN-110249 |
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author | Nomura, Keiko Kazui, Hiroaki Tokunaga, Hiromasa Hirata, Masayuki Goto, Tetsu Goto, Yuko Hashimoto, Naoya Yoshimine, Toshiki Takeda, Masatoshi |
author_facet | Nomura, Keiko Kazui, Hiroaki Tokunaga, Hiromasa Hirata, Masayuki Goto, Tetsu Goto, Yuko Hashimoto, Naoya Yoshimine, Toshiki Takeda, Masatoshi |
author_sort | Nomura, Keiko |
collection | PubMed |
description | How the dominant uncinate fasciculus (UF) contributes to naming performance is uncertain. In this case report, a patient with an astrocytoma near the dominant UF was given a picture-naming task during intraoperative electrical stimulation in order to resect as much tumourous tissues as possible without impairing the dominant UF function. Here we report that the stimulations with the picture-naming task also provided some insights into how the dominant UF contributes to naming performance. The stimulation induced naming difficulty, verbal paraphasia, and recurrent and continuous perseveration. Moreover, just after producing the incorrect responses, the patient displayed continuous perseveration even though the stimulation had ended. The left UF connects to the inferior frontal lobe, which is necessary for word production, so that the naming difficulty appears to be the result of disrupted word production caused by electrical stimulation of the dominant UF. The verbal paraphasia appears to be due to the failure to select the correct word from semantic memory and the failure to suppress the incorrect word. The left UF is associated with working memory, which plays an important role in recurrent perseveration. The continuous perseveration appears to be due to disturbances in word production and a failure to inhibit an appropriate response. These findings in this case suggest that the dominant UF has multiple roles in the naming of objects. |
format | Online Article Text |
id | pubmed-5215405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-52154052017-03-23 Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour Nomura, Keiko Kazui, Hiroaki Tokunaga, Hiromasa Hirata, Masayuki Goto, Tetsu Goto, Yuko Hashimoto, Naoya Yoshimine, Toshiki Takeda, Masatoshi Behav Neurol Case Report How the dominant uncinate fasciculus (UF) contributes to naming performance is uncertain. In this case report, a patient with an astrocytoma near the dominant UF was given a picture-naming task during intraoperative electrical stimulation in order to resect as much tumourous tissues as possible without impairing the dominant UF function. Here we report that the stimulations with the picture-naming task also provided some insights into how the dominant UF contributes to naming performance. The stimulation induced naming difficulty, verbal paraphasia, and recurrent and continuous perseveration. Moreover, just after producing the incorrect responses, the patient displayed continuous perseveration even though the stimulation had ended. The left UF connects to the inferior frontal lobe, which is necessary for word production, so that the naming difficulty appears to be the result of disrupted word production caused by electrical stimulation of the dominant UF. The verbal paraphasia appears to be due to the failure to select the correct word from semantic memory and the failure to suppress the incorrect word. The left UF is associated with working memory, which plays an important role in recurrent perseveration. The continuous perseveration appears to be due to disturbances in word production and a failure to inhibit an appropriate response. These findings in this case suggest that the dominant UF has multiple roles in the naming of objects. IOS Press 2013 /pmc/articles/PMC5215405/ /pubmed/23242348 http://dx.doi.org/10.3233/BEN-110249 Text en Copyright © 2013 Hindawi Publishing Corporation and the authors. http://creativecommons.org/licenses/by/3.0 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Nomura, Keiko Kazui, Hiroaki Tokunaga, Hiromasa Hirata, Masayuki Goto, Tetsu Goto, Yuko Hashimoto, Naoya Yoshimine, Toshiki Takeda, Masatoshi Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour |
title | Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour |
title_full | Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour |
title_fullStr | Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour |
title_full_unstemmed | Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour |
title_short | Possible Roles of the Dominant Uncinate Fasciculus in Naming Objects: A Case Report of Intraoperative Electrical Stimulation on a Patient with a Brain Tumour |
title_sort | possible roles of the dominant uncinate fasciculus in naming objects: a case report of intraoperative electrical stimulation on a patient with a brain tumour |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215405/ https://www.ncbi.nlm.nih.gov/pubmed/23242348 http://dx.doi.org/10.3233/BEN-110249 |
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