Perturbed proteostasis in autism spectrum disorders

Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes enc...

Descripción completa

Detalles Bibliográficos
Autores principales: Louros, Susana R., Osterweil, Emily K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Mini Review Series: Synaptic Function and Dysfunction in Brain Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215415/
https://www.ncbi.nlm.nih.gov/pubmed/27365114
http://dx.doi.org/10.1111/jnc.13723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215415/
https://www.ncbi.nlm.nih.gov/pubmed/27365114
http://dx.doi.org/10.1111/jnc.13723

Ejemplares similares