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Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures
Differentiated neurons can be rapidly acquired, within days, by inducing stem cells to express neurogenic transcription factors. We developed a protocol to maintain long-term cultures of human neurons, called iNGNs, which are obtained by inducing Neurogenin-1 and Neurogenin-2 expression in induced p...
Autores principales: | Lam, Rebecca S., Töpfer, Felix M., Wood, Phillip G., Busskamp, Volker, Bamberg, Ernst |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215418/ https://www.ncbi.nlm.nih.gov/pubmed/28052116 http://dx.doi.org/10.1371/journal.pone.0169506 |
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