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High Shear Stresses under Exercise Condition Destroy Circulating Tumor Cells in a Microfluidic System

Circulating tumor cells (CTCs) are the primary targets of cancer treatment as they cause distal metastasis. However, how CTCs response to exercise-induced high shear stress is largely unknown. To study the effects of hemodynamic microenvironment on CTCs, we designed a microfluidic circulatory system...

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Detalles Bibliográficos
Autores principales: Regmi, Sagar, Fu, Afu, Luo, Kathy Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215453/
https://www.ncbi.nlm.nih.gov/pubmed/28054593
http://dx.doi.org/10.1038/srep39975