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Generation of Human Corneal Endothelial Cells via In Vitro Ocular Lineage Restriction of Pluripotent Stem Cells

PURPOSE: We generate a renewable supply of corneal endothelial cells (CEC) from human pluripotent stem cells (PSCs) under defined culture conditions. METHODS: Corneal endothelial cell induction was driven by small molecules in a stepwise fashion of lineage specification. During the initial phase, PS...

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Detalles Bibliográficos
Autores principales: Zhao, Jiagang J., Afshari, Natalie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215466/
https://www.ncbi.nlm.nih.gov/pubmed/28002562
http://dx.doi.org/10.1167/iovs.16-20024