A Novel Zn(2)-Cys(6) Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions

Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an increasing incidence of drug resistance. This situation is further complicated by the finding that strains resistant to azoles, the major antifungal drugs for aspergillosis, have been widely disseminated across...

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Detalles Bibliográficos
Autores principales: Hagiwara, Daisuke, Miura, Daisuke, Shimizu, Kiminori, Paul, Sanjoy, Ohba, Ayumi, Gonoi, Tohru, Watanabe, Akira, Kamei, Katsuhiko, Shintani, Takahiro, Moye-Rowley, W. Scott, Kawamoto, Susumu, Gomi, Katsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215518/
https://www.ncbi.nlm.nih.gov/pubmed/28052140
http://dx.doi.org/10.1371/journal.ppat.1006096

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