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Real‐time monitoring and control of the load phase of a protein A capture step

The load phase in preparative Protein A capture steps is commonly not controlled in real‐time. The load volume is generally based on an offline quantification of the monoclonal antibody (mAb) prior to loading and on a conservative column capacity determined by resin‐life time studies. While this res...

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Detalles Bibliográficos
Autores principales:	Rüdt, Matthias, Brestrich, Nina, Rolinger, Laura, Hubbuch, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215519/ https://www.ncbi.nlm.nih.gov/pubmed/27543789 http://dx.doi.org/10.1002/bit.26078

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