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Effects of baseline abdominal pain and bloating on response to lubiprostone in patients with irritable bowel syndrome with constipation

BACKGROUND: Lubiprostone (8 μg b.d.) received US Food and Drug Administration (FDA) approval in 2008 for the treatment of constipation‐predominant irritable bowel syndrome (IBS‐C) in women aged ≥18 years. In 2012, the FDA issued new guidance for IBS‐C clinical trials, recommending a composite endpoi...

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Detalles Bibliográficos
Autores principales:	Chang, L., Chey, W. D., Drossman, D., Losch‐Beridon, T., Wang, M., Lichtlen, P., Mareya, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Lubiprostone and Irritable Bowel Syndrome
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215520/ https://www.ncbi.nlm.nih.gov/pubmed/27669680 http://dx.doi.org/10.1111/apt.13807

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