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Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis

BACKGROUND: Different extents and locations of acetabular cartilage defect have been supposed to be a major cause of undesirable outcomes of periacetabular osteotomy (PAO) in patients with developmental dysplasia of the hip (DDH). This study aimed to verify whether different locations of cartilage d...

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Autores principales: Xu, Meng, Qu, Wenrui, Wang, Yanbing, Zhong, Lei, Zhu, Zhe, Li, Wei, Zhao, Xin, Wang, Jincheng, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215568/
https://www.ncbi.nlm.nih.gov/pubmed/28017958
http://dx.doi.org/10.12659/MSM.902724
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author Xu, Meng
Qu, Wenrui
Wang, Yanbing
Zhong, Lei
Zhu, Zhe
Li, Wei
Zhao, Xin
Wang, Jincheng
Sun, Yu
author_facet Xu, Meng
Qu, Wenrui
Wang, Yanbing
Zhong, Lei
Zhu, Zhe
Li, Wei
Zhao, Xin
Wang, Jincheng
Sun, Yu
author_sort Xu, Meng
collection PubMed
description BACKGROUND: Different extents and locations of acetabular cartilage defect have been supposed to be a major cause of undesirable outcomes of periacetabular osteotomy (PAO) in patients with developmental dysplasia of the hip (DDH). This study aimed to verify whether different locations of cartilage deficiency affect the biomechanical environment in a three-dimensional model utilizing finite element analysis (FEA). MATERIAL/METHODS: We developed 3 DDH models – DDH-1 (normal shape), DDH-2 (superior defect), and DDH-3 (anterosuperior defect) – by deforming from a normal hip model. We also developed 3 PAO models – PAO-1, PAO-2, and PAO-3 – through rotating osteotomized fragments. RESULTS: The maximum von Mises stress in the normal hip was 13.06 MPa. In the DDH-1 model, the maximum value on the load-bearing area decreased from 15.49 MPa pre-PAO to 14.28 MPa post-PAO, while stresses in the DDH-2 and DDH-3 models were higher than in the DDH-1 model, both pre-PAO and post-PAO (30.46 MPa to 26.04 MPa for DDH-2; 33.89 MPa to 27.48 MPa for DDH-3). CONCLUSIONS: This study shows that, both pre- and post-PAO, different types of cartilage deficiency affect the biomechanical environment. Furthermore, in dysplastic hips, obtaining accurate three-dimensional information about the acetabular cartilage can contribute substantially to PAO decision making.
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spelling pubmed-52155682017-01-17 Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis Xu, Meng Qu, Wenrui Wang, Yanbing Zhong, Lei Zhu, Zhe Li, Wei Zhao, Xin Wang, Jincheng Sun, Yu Med Sci Monit Lab/In Vitro Research BACKGROUND: Different extents and locations of acetabular cartilage defect have been supposed to be a major cause of undesirable outcomes of periacetabular osteotomy (PAO) in patients with developmental dysplasia of the hip (DDH). This study aimed to verify whether different locations of cartilage deficiency affect the biomechanical environment in a three-dimensional model utilizing finite element analysis (FEA). MATERIAL/METHODS: We developed 3 DDH models – DDH-1 (normal shape), DDH-2 (superior defect), and DDH-3 (anterosuperior defect) – by deforming from a normal hip model. We also developed 3 PAO models – PAO-1, PAO-2, and PAO-3 – through rotating osteotomized fragments. RESULTS: The maximum von Mises stress in the normal hip was 13.06 MPa. In the DDH-1 model, the maximum value on the load-bearing area decreased from 15.49 MPa pre-PAO to 14.28 MPa post-PAO, while stresses in the DDH-2 and DDH-3 models were higher than in the DDH-1 model, both pre-PAO and post-PAO (30.46 MPa to 26.04 MPa for DDH-2; 33.89 MPa to 27.48 MPa for DDH-3). CONCLUSIONS: This study shows that, both pre- and post-PAO, different types of cartilage deficiency affect the biomechanical environment. Furthermore, in dysplastic hips, obtaining accurate three-dimensional information about the acetabular cartilage can contribute substantially to PAO decision making. International Scientific Literature, Inc. 2016-12-26 /pmc/articles/PMC5215568/ /pubmed/28017958 http://dx.doi.org/10.12659/MSM.902724 Text en © Med Sci Monit, 2016 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
spellingShingle Lab/In Vitro Research
Xu, Meng
Qu, Wenrui
Wang, Yanbing
Zhong, Lei
Zhu, Zhe
Li, Wei
Zhao, Xin
Wang, Jincheng
Sun, Yu
Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis
title Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis
title_full Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis
title_fullStr Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis
title_full_unstemmed Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis
title_short Theoretical Implications of Periacetabular Osteotomy in Various Dysplastic Acetabular Cartilage Defects as Determined by Finite Element Analysis
title_sort theoretical implications of periacetabular osteotomy in various dysplastic acetabular cartilage defects as determined by finite element analysis
topic Lab/In Vitro Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215568/
https://www.ncbi.nlm.nih.gov/pubmed/28017958
http://dx.doi.org/10.12659/MSM.902724
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