Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects of the mTOR Inhibitor Everolimus against Melanoma

The PI3K/mTOR/AKT pathway is activated in most melanomas, but mTOR inhibitors used singly have limited activity against advanced melanomas. The application of nanosecond pulsed electric fields (nsPEFs) is a promising cancer therapy approach. In this study, we evaluated the synergistic anti-tumour ef...

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Detalles Bibliográficos
Autores principales: Dai, Jie, Wu, Shan, Kong, Yan, Chi, Zhihong, Si, Lu, Sheng, Xinan, Cui, Chuanliang, Fang, Jing, Zhang, Jue, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215571/
https://www.ncbi.nlm.nih.gov/pubmed/28054548
http://dx.doi.org/10.1038/srep39597

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