Topiramate for Abnormal Eating Behaviour in Frontotemporal Dementia

Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that is associated with anorexia and weight loss and has been used to treat binge eating disorder and bulimia nervosa. This report describes a man with frontotemporal dementia, behavioural variant, associated with abnormal eating be...

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Detalles Bibliográficos
Autores principales: Singam, Colin, Walterfang, Mark, Mocellin, Ramon, Evans, Andrew, Velakoulis, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2013
Materias:
Clinical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215572/
https://www.ncbi.nlm.nih.gov/pubmed/23548883
http://dx.doi.org/10.3233/BEN-120257
Descripción
Sumario:Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that is associated with anorexia and weight loss and has been used to treat binge eating disorder and bulimia nervosa. This report describes a man with frontotemporal dementia, behavioural variant, associated with abnormal eating behaviour which appeared to respond to topiramate. We review the physiological basis of abnormal eating behaviour in frontotemporal dementia and explore possible mechanisms of action by which topiramate may modify eating behaviour in this condition.

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