Cargando…

Autophagy Is an Innate Mechanism Associated with Leprosy Polarization

Leprosy is a chronic infectious disease that may present different clinical forms according to the immune response of the host. Levels of IFN-γ are significantly raised in paucibacillary tuberculoid (T-lep) when compared with multibacillary lepromatous (L-lep) patients. IFN-γ primes macrophages for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Silva, Bruno Jorge de Andrade, Barbosa, Mayara Garcia de Mattos, Andrade, Priscila Ribeiro, Ferreira, Helen, Nery, José Augusto da Costa, Côrte-Real, Suzana, da Silva, Gilberto Marcelo Sperandio, Rosa, Patricia Sammarco, Fabri, Mario, Sarno, Euzenir Nunes, Pinheiro, Roberta Olmo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215777/ https://www.ncbi.nlm.nih.gov/pubmed/28056107 http://dx.doi.org/10.1371/journal.ppat.1006103

Ejemplares similares

Autophagy-Associated IL-15 Production Is Involved in the Pathogenesis of Leprosy Type 1 Reaction
por: Silva, Bruno Jorge de Andrade, et al.
Publicado: (2021)

Autophagy Impairment Is Associated With Increased Inflammasome Activation and Reversal Reaction Development in Multibacillary Leprosy
por: de Mattos Barbosa, Mayara Garcia, et al.
Publicado: (2018)

Innate Immune Responses in Leprosy
por: Pinheiro, Roberta Olmo, et al.
Publicado: (2018)

Gene Expression Profile of Mycobacterium leprae Contribution in the Pathology of Leprosy Neuropathy
por: de Souza, Beatriz Junqueira, et al.
Publicado: (2022)

Macrophage Polarization in Leprosy–HIV Co-infected Patients
por: da Silva, Tatiana Pereira, et al.
Publicado: (2020)

Potential Role of CXCL10 in Monitoring Response to Treatment in Leprosy Patients
por: Ferreira, Helen, et al.
Publicado: (2021)

Arginase 1 is a marker of protection against illness in contacts of leprosy patients
por: da Silva Prata, Rhana Berto, et al.
Publicado: (2022)

Correlation between Central Memory T Cell Expression and Proinflammatory Cytokine Production with Clinical Presentation of Multibacillary Leprosy Relapse
por: Esquenazi, Danuza, et al.
Publicado: (2015)

Correction: Correlation between Central Memory T Cell Expression and Proinflammatory Cytokine Production with Clinical Presentation of Multibacillary Leprosy Relapse
por: Esquenazi, Danuza, et al.
Publicado: (2015)

Genetic polymorphisms of the IL6 and NOD2 genes are risk factors for inflammatory reactions in leprosy
por: Sales-Marques, Carolinne, et al.
Publicado: (2017)

Case report: Injected corticosteroids for treating leprosy isolated neuritis
por: Spitz, Clarissa Neves, et al.
Publicado: (2023)

A new paradigm for leprosy diagnosis based on host gene expression
por: Leal-Calvo, Thyago, et al.
Publicado: (2021)

Clinical prediction rules for the diagnosis of neuritis in leprosy
por: Giesel, Louise Mara, et al.
Publicado: (2021)

Cytokine Levels in Neural Pain in Leprosy
por: Angst, Débora Bartzen Moraes, et al.
Publicado: (2020)

Chemoprophylaxis of leprosy with rifampicin in contacts of multibacillary patients: study protocol for a randomized controlled trial
por: dos Santos, Daiane Santos, et al.
Publicado: (2018)

Circulating levels of insulin-like growth factor-I (IGF-I) correlate with disease status in leprosy
por: Rodrigues, Luciana Silva, et al.
Publicado: (2011)

Psychometric assessment of the EMIC Stigma Scale for Brazilians affected by leprosy
por: Frota da Rocha Morgado, Fabiane, et al.
Publicado: (2020)

Neutrophils in Leprosy
por: Schmitz, Veronica, et al.
Publicado: (2019)

Kinship and Leprosy in the Contacts of Leprosy Patients: Cohort at the Souza Araújo Outpatient Clinic, Rio de Janeiro, RJ, 1987–2010
por: dos Santos, Daiane Santos, et al.
Publicado: (2013)

Utility of immunoglobulin isotypes against LID-1 and NDO-LID for, particularly IgG1, confirming the diagnosis of multibacillary leprosy
por: Marçal, Pedro Henrique Ferreira, et al.
Publicado: (2018)

Cross-cultural adaptation of the EMIC Stigma Scale for people with leprosy in Brazil
por: Morgado, Fabiane Frota da Rocha, et al.
Publicado: (2017)

Multibacillary leprosy by population groups in Brazil: Lessons from an observational study
por: Nobre, Mauricio Lisboa, et al.
Publicado: (2017)

Presence of Senescent and Memory CD8+ Leukocytes as Immunocenescence Markers in Skin Lesions of Elderly Leprosy Patients
por: da Silva, Pedro Henrique Lopes, et al.
Publicado: (2021)

Increased oxidative stress in elderly leprosy patients is related to age but not to bacillary load
por: da Silva, Pedro Henrique Lopes, et al.
Publicado: (2021)

Gene expression patterns associated with multidrug therapy in multibacillary leprosy
por: Ferreira, Helen, et al.
Publicado: (2022)

Blood coagulation abnormalities in multibacillary leprosy patients
por: da Silva, Débora Santos, et al.
Publicado: (2018)

Kynurenines in the Pathogenesis of Peripheral Neuropathy During Leprosy and COVID-19
por: de Oliveira, Jéssica Araujo da Paixão, et al.
Publicado: (2022)

Serum IgA Antibodies Specific to M. leprae Antigens as Biomarkers for Leprosy Detection and Household Contact Tracking
por: Silva, Kyssia Karen de Paiva e, et al.
Publicado: (2021)

Role of T(EFFECTOR/MEMORY) Cells, TBX21 Gene Expression and T-Cell Homing Receptor on Type 1 Reaction in Borderline Lepromatous Leprosy Patients
por: dos Santos, Luciana Nahar, et al.
Publicado: (2016)

Progression of leprosy disability after discharge: is multidrug therapy enough?
por: Sales, Anna Maria, et al.
Publicado: (2013)

Functional biomarker signatures of circulating T-cells and its association with distinct clinical status of leprosy patients and their respective household contacts
por: Marçal, Pedro Henrique Ferreira, et al.
Publicado: (2020)

Fibrosis: a distinguishing feature in the pathology of neural leprosy
por: Antunes, Sérgio Luiz Gomes, et al.
Publicado: (2019)

Diagnostic challenges of single plaque-like lesion paucibacillary leprosy
por: Barbieri, Raquel Rodrigues, et al.
Publicado: (2014)

Leprosy incidence and risk estimates in a 33-year contact cohort of leprosy patients
por: Hacker, Mariana Andrea, et al.
Publicado: (2021)

Interruption of persistent exposure to leprosy combined or not with recent BCG vaccination enhances the response to Mycobacterium leprae specific antigens
por: de Carvalho, Fernanda Marques, et al.
Publicado: (2017)

Neutrophil extracellular traps contribute to the pathogenesis of leprosy type 2 reactions
por: da Silva, Camila Oliveira, et al.
Publicado: (2019)

Evaluation of Cellular Phenotypes Implicated in Immunopathogenesis and Monitoring Immune Reconstitution Inflammatory Syndrome in HIV/Leprosy Cases
por: Giacoia-Gripp, Carmem Beatriz Wagner, et al.
Publicado: (2011)

Author Correction: Leprosy incidence and risk estimates in a 33-year contact cohort of leprosy patients
por: Hacker, Mariana Andrea, et al.
Publicado: (2021)

Autophagy as a Target for Drug Development Of Skin Infection Caused by Mycobacteria
por: Bittencourt, Tamiris Lameira, et al.
Publicado: (2021)

Impact of a Reference Center on Leprosy Control under a Decentralized Public Health Care Policy in Brazil
por: Barbieri, Raquel Rodrigues, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ktdfnk930231i5clt26hhtj07p