ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication

ASC (apoptosis-associated speck-like protein containing a CARD) is a key adaptor molecule of inflammasomes that mediates inflammatory and apoptotic signals. Aberrant methylation-induced silencing of ASC has been observed in a variety of cancer cells, thus implicating ASC in tumor suppression, althou...

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Detalles Bibliográficos
Autores principales: Kitazawa, Masato, Hida, Shigeaki, Fujii, Chifumi, Taniguchi, Shun’ichiro, Ito, Kensuke, Matsumura, Tomio, Okada, Nagisa, Sakaizawa, Takashi, Kobayashi, Akira, Takeoka, Michiko, Miyagawa, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215782/
https://www.ncbi.nlm.nih.gov/pubmed/28056049
http://dx.doi.org/10.1371/journal.pone.0169340

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