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The bacterial dicarboxylate transporter, VcINDY, uses a two-domain elevator-type mechanism

Secondary transporters use alternating access mechanisms to couple uphill substrate movement to downhill ion flux. Most known transporters utilize a “rocking bundle” motion, where the protein moves around an immobile substrate binding site. However, the glutamate transporter homolog, Glt(Ph), transl...

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Detalles Bibliográficos
Autores principales: Mulligan, Christopher, Fenollar-Ferrer, Cristina, Fitzgerald, Gabriel A., Vergara-Jaque, Ariela, Kaufmann, Desirée, Li, Yan, Forrest, Lucy R., Mindell, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215794/
https://www.ncbi.nlm.nih.gov/pubmed/26828963
http://dx.doi.org/10.1038/nsmb.3166

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