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Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival
Autophagy is a cellular self-eating process essential for stress response and maintaining tissue homeostasis by lysosomal degradation of unwanted or damaged proteins and organelles. Here, we show that cells with defective mitochondria induce autophagy to promote cell survival through activating the...
Autores principales: | Zhao, Baozhong, Qiang, Lei, Joseph, Joy, Kalyanaraman, Balaraman, Viollet, Benoit, He, Yu-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215801/ https://www.ncbi.nlm.nih.gov/pubmed/28066797 http://dx.doi.org/10.1016/j.gendis.2015.12.002 |
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