HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes

INTRODUCTION: Telomerase repairs the telomeric ends of chromosomes and is active in nearly all malignant cells. Hepatitis C virus (HCV) is known to be oncogenic and potential interactions with the telomerase system require further study. We determined the effects of HCV infection on human telomerase...

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Detalles Bibliográficos
Autores principales: Zhu, Zhaowen, Tran, Huy, Mathahs, M. Meleah, Moninger, Thomas O., Schmidt, Warren N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215869/
https://www.ncbi.nlm.nih.gov/pubmed/28056029
http://dx.doi.org/10.1371/journal.pone.0166853

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