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Identification of genetic variants associated with susceptibility to West Nile virus neuroinvasive disease

West Nile virus (WNV) infection results in a diverse spectrum of outcomes, and host genetics are likely to influence susceptibility to neuroinvasive disease (WNND). We performed whole exome sequencing of 44 individuals with WNND and identified alleles associated with severe disease by variant filtra...

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Detalles Bibliográficos
Autores principales: Long, Dustin, Deng, Xutao, Singh, Pardeep, Loeb, Mark, Lauring, Adam S., Seielstad, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215919/
https://www.ncbi.nlm.nih.gov/pubmed/27170560
http://dx.doi.org/10.1038/gene.2016.21