Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks

SB 9200, an orally bioavailable dinucleotide, activates the viral sensor proteins, retinoic acid-inducible gene 1 (RIG-I) and nucleotide-binding oligomerization domain-containing protein 2 (NOD2) causing the induction of the interferon (IFN) signaling cascade for antiviral defense. The present study...

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Detalles Bibliográficos
Autores principales: Suresh, Manasa, Korolowicz, Kyle E., Balarezo, Maria, Iyer, Radhakrishnan P., Padmanabhan, Seetharamaiyer, Cleary, Dillon, Gimi, Rayomand, Sheri, Anjaneyulu, Yon, Changsuek, Kallakury, Bhaskar V., Tucker, Robin D., Afdhal, Nezam, Menne, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215947/
https://www.ncbi.nlm.nih.gov/pubmed/28056062
http://dx.doi.org/10.1371/journal.pone.0169631

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