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A balance between elongation and trimming regulates telomere stability in stem cells

Telomere length maintenance ensures self-renewal of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), however the mechanisms governing telomere length homeostasis in these cell types are unclear. Here, we report that telomere length is determined by the balance between t...

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Detalles Bibliográficos
Autores principales: Rivera, Teresa, Haggblom, Candy, Cosconati, Sandro, Karlseder, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215970/
https://www.ncbi.nlm.nih.gov/pubmed/27918544
http://dx.doi.org/10.1038/nsmb.3335

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