Neuroprotective effects of intravenous immunoglobulin are mediated through inhibition of complement activation and apoptosis in a rat model of sepsis

BACKGROUND: Intravenous (IV) immunoglobulin (Ig) treatment is known to alleviate behavioral deficits and increase survival in the experimentally induced model of sepsis. To delineate the mechanisms by which IVIg treatment prevents neuronal dysfunction, an array of immunological and apoptosis markers...

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Detalles Bibliográficos
Autores principales: Esen, Figen, Orhun, Gunseli, Ozcan, Perihan Ergin, Senturk, Evren, Kucukerden, Melike, Giris, Murat, Akcan, Ugur, Yilmaz, Canan Ugur, Orhan, Nurcan, Arican, Nadir, Kaya, Mehmet, Gazioglu, Sema Bilgic, Tuzun, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215999/
https://www.ncbi.nlm.nih.gov/pubmed/28058672
http://dx.doi.org/10.1186/s40635-016-0114-1

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