Cargando…

Death receptor 6 contributes to autoimmunity in lupus-prone mice

Expansion of autoreactive follicular helper T (Tfh) cells is tightly restricted to prevent induction of autoantibody-dependent immunological diseases, such as systemic lupus erythematosus (SLE). Here we show expression of an orphan immune regulator, death receptor 6 (DR6/TNFRSF21), on a population o...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujikura, Daisuke, Ikesue, Masahiro, Endo, Tsutomu, Chiba, Satoko, Higashi, Hideaki, Uede, Toshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216082/
https://www.ncbi.nlm.nih.gov/pubmed/28045014
http://dx.doi.org/10.1038/ncomms13957

Ejemplares similares