JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

A stable pool of morphogen-producing cells is critical for the development of any organ or tissue. Here we present evidence that JAK/STAT signalling in the Drosophila wing promotes the cycling and survival of Hedgehog-producing cells, thereby allowing the stable localization of the nearby BMP/Dpp-or...

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Detalles Bibliográficos
Autores principales: Recasens-Alvarez, Carles, Ferreira, Ana, Milán, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216089/
https://www.ncbi.nlm.nih.gov/pubmed/28045022
http://dx.doi.org/10.1038/ncomms13815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216089/
https://www.ncbi.nlm.nih.gov/pubmed/28045022
http://dx.doi.org/10.1038/ncomms13815

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