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JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
A stable pool of morphogen-producing cells is critical for the development of any organ or tissue. Here we present evidence that JAK/STAT signalling in the Drosophila wing promotes the cycling and survival of Hedgehog-producing cells, thereby allowing the stable localization of the nearby BMP/Dpp-or...
Autores principales: | Recasens-Alvarez, Carles, Ferreira, Ana, Milán, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216089/ https://www.ncbi.nlm.nih.gov/pubmed/28045022 http://dx.doi.org/10.1038/ncomms13815 |
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