Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

Apoptosis is a genetically regulated cell suicide programme mediated by activation of the effector caspases 3, 6 and 7. If apoptotic cells are not scavenged, they progress to a lytic and inflammatory phase called secondary necrosis. The mechanism by which this occurs is unknown. Here we show that ca...

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Detalles Bibliográficos
Autores principales: Rogers, Corey, Fernandes-Alnemri, Teresa, Mayes, Lindsey, Alnemri, Diana, Cingolani, Gino, Alnemri, Emad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216131/
https://www.ncbi.nlm.nih.gov/pubmed/28045099
http://dx.doi.org/10.1038/ncomms14128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216131/
https://www.ncbi.nlm.nih.gov/pubmed/28045099
http://dx.doi.org/10.1038/ncomms14128

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