Restoration of the Hypothalamic-pituitary-adrenal Response to Hypoglycemia in Type 2 Diabetes by Avoiding Chronic Hypoglycemia

An impaired ability to sense and respond to drug-induced hypoglycemia is a common and serious complication in diabetic patients. The hypothalamic-pituitary-adrenal (HPA) axis activity plays a critical role in the counterregulatory response to hypoglycemia. We herein report a case that experienced re...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuda, Shin-ichi, Konishi, Kazunori, Otoda, Toshiki, Nagai, Takako, Takeda-Watanabe, Ai, Kanasaki, Megumi, Kitada, Munehiro, Nakagawa, Atsushi, Nishizawa, Makoto, Kanasaki, Keizo, Koya, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216145/
https://www.ncbi.nlm.nih.gov/pubmed/27904111
Descripción
Sumario:An impaired ability to sense and respond to drug-induced hypoglycemia is a common and serious complication in diabetic patients. The hypothalamic-pituitary-adrenal (HPA) axis activity plays a critical role in the counterregulatory response to hypoglycemia. We herein report a case that experienced restoration of a blunted HPA axis by avoiding hypoglycemia with the use of the DPP-4 inhibitor sitagliptin.

Ejemplares similares