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Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors
Viral vector mediated gene therapy has become commonplace in clinical trials for a wide range of inherited disorders. Successful gene transfer depends on a number of factors, of which tissue tropism is among the most important. To date, definitive mapping of the spatial and temporal distribution of...
Autores principales: | Kothari, P., De, B. P., He, B., Chen, A., Chiuchiolo, M. J., Kim, D., Nikolopoulou, A., Amor-Coarasa, A., Dyke, J. P., Voss, H. U., Kaminsky, S. M., Foley, C. P., Vallabhajosula, S., Hu, B., DiMagno, S. G., Sondhi, D., Crystal, R. G., Babich, J. W., Ballon, D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216390/ https://www.ncbi.nlm.nih.gov/pubmed/28059103 http://dx.doi.org/10.1038/srep39594 |
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