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A novel role for the DNA repair gene Rad51 in Netrin-1 signalling

Mutations in RAD51 have recently been linked to human Congenital Mirror Movements (CMM), a developmental disorder of the motor system. The only gene previously linked to CMM encodes the Netrin-1 receptor DCC, which is important for formation of corticospinal and callosal axon tracts. Thus, we hypoth...

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Detalles Bibliográficos
Autores principales: Glendining, K. A., Markie, D., Gardner, R. J. M., Franz, E. A., Robertson, S. P., Jasoni, C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216413/
https://www.ncbi.nlm.nih.gov/pubmed/28057929
http://dx.doi.org/10.1038/srep39823

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